The coronary microcirculation in sepsis: not of micro-importance
[No abstract - showing first paragraph]
The coronary arterial system consists of a continuous network of functionally distinct vessels of decreasing size. The epicardial arteries (>500 μm) have primarily a conductance function and, therefore, physiologically offer minimal resistance to flow. The microcirculation, including pre-arterioles (100 to 500 μm) and arterioles (<100 μm), on the other hand, is the main active determinant of resistance within the coronary tree, responsible for the metabolic regulation of regional blood flow to the myocardium.
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