Microvascular dysfunction in septic and dengue shock: Pathophysiology and implications for clinical management

Angela McBride, Ho Q Chanh, John F Fraser, Sophie Yacoub, Nchafatso G Obonyo

Abstract


[No abstract, showing first paragraph of article]

The microcirculation is the terminal vascular network of the systemic circulation, whose primary function is to distribute oxygen to, and remove metabolic by-products from living cells. In health, tissue perfusion is regulated by control of microvascular tone and endothelial permeability. In states of shock, however, there is a mismatch between demand for, and delivery or utilisation of oxygen in the tissues.


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DOI: http://dx.doi.org/10.21542/gcsp.2020.29

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Copyright (c) 2020 Angela McBride, Ho Q Chanh, James F Fraser, Sophie Yacoub, Nchafatso G Obonyo

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