Progress in the understanding and management of pulmonary arterial hypertension

A M Chakrabati, J A Mitchell, S J Wort


[first paragraph of article]

In 1981 the “Patient Registry for the Characterization of Primary Pulmonary Hypertension” was set up, supported by the National Heart, Lung and Blood Institute, and recruited 194 patients across
32 clinical centres over 4 years in the United States. The estimated median survival of these incident cases of primary pulmonary hypertension (which approximates to what we would now term idiopathic pulmonary arterial hypertension, IPAH) was 2.8 years, with a 68% survival rate at 1 year, 48% at 3 years and 35% at 5 years. 

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Copyright (c) 2017 A M Chakrabati, J A Mitchell, S J Wort

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