Progress in the understanding and management of pulmonary arterial hypertension

Authors

  • A M Chakrabati Royal Brompton Hospital, London, UK
  • J A Mitchell National Heart and Lung Institute, Imperial College London, UK
  • S J Wort Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, UK

Abstract

[first paragraph of article]

In 1981 the “Patient Registry for the Characterization of Primary Pulmonary Hypertension” was set up, supported by the National Heart, Lung and Blood Institute, and recruited 194 patients across
32 clinical centres over 4 years in the United States. The estimated median survival of these incident cases of primary pulmonary hypertension (which approximates to what we would now term idiopathic pulmonary arterial hypertension, IPAH) was 2.8 years, with a 68% survival rate at 1 year, 48% at 3 years and 35% at 5 years. 

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Published

2017-07-07

Issue

Vol. 2015 No. 1 (2015)

Section

Mechanisms of disease

License

This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.