Reprogramming for cardiac regeneration

Christophe Michel Raynaud, Faizzan Syed Ahmad, Mona Allouba, Haissam Abou-Saleh, Kathy O Lui, Magdi Yacoub

Abstract


Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitroand in vivocardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, and their promises and future challenges before clinical entry, are all discussed here.

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Copyright (c) 2017 Christophe Michel Raynaud, Faizzan Syed Ahmad, Mona Allouba, Haissam Abou-Saleh, Kathy O Lui, Magdi Yacoub

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This work is licensed under a Creative Commons Attribution 4.0 International License.